中国神经再生研究(英文版) ›› 2023, Vol. 18 ›› Issue (9): 1950-1951.doi: 10.4103/1673-5374.366498

• 观点:退行性病与再生 • 上一篇    下一篇

髓鞘糖脂硫酸盐在多发性硬化症发病机制中的免疫学作用

  

  • 出版日期:2023-09-15 发布日期:2023-03-06

Immunological role of sulfatide in the pathogenesis of multiple sclerosis

Mio Hamatani, Takayuki Kondo*   

  1. Institute for the Advanced Study of Human Biology, Kyoto University, Kyoto, Japan (Hamatani M)
    Department of Neurology, Kansai Medical University Medical Center, Moriguchi, Japan (Kondo T)
  • Online:2023-09-15 Published:2023-03-06
  • Contact: Takayuki Kondo, MD, PhD, takakon78@hotmail.com.

摘要: https://orcid.org/0000-0003-0331-6476 (Mio Hamatani)
https://orcid.org/0000-0001-7048-9401 (Takayuki Kondo)

Abstract: Multiple sclerosis (MS) is a chronic inflammatory demyelinating disease of the central nervous system. A certain population of patients with MS present with a relapse-remitting disease course (RRMS) during the early phase and eventually advance to a progressive course (PMS). While immune modulation therapies have recently seen tremendous success in RRMS, our limited knowledge of pathogenesis hampers the development of effective treatments for PMS.