神经损伤与修复

    Iron, the endolysosomal system and neuroinflammation: a matter of balance
  • Figure 1|Aging- and disease-associated endolysosomal malfunction generates functional iron deficiency associated with iron accumulation and neuroinflammation. 

    A link between iron dysregulation, endolysosomal acidification and inflammation: Based on the evidence discussed above, we propose a model that links iron dysregulation, both in neurons and microglia, with endolysosomal acidification, mitochondrial dysfunction and neuroinflammation (Figure 1).


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  • 发布日期: 2021-12-08  浏览: 460
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