神经损伤与修复

Emerging role of lysosomal calcium store as a hub of neuroprotection

• Figure 1｜The lysosome-centered theory. 

  

  In conclusion, we suggest that lysosome and its machinery may be considered a hub of neuroprotection (Figure 1) since: (i) the tiny organelle stabilizes the global ionic balance in virtue of the strict interaction with the ER, and (ii) it controls the autophagic process through TFEB.

  
  

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发布日期： 2021-12-17  浏览： 500