Figure 4| Histological changes after SCI.
The volume of a post-traumatic intramedullary cyst and the extent of post-traumatic astrogliosis were assessed on GFAP-stained spinal cord cross sections 6 weeks after injury (Figure 4A), while CSPG-stained sections were used to quantify the extent of post-traumatic CS-GAG deposition (Figure 4B). Intramedullary cysts could only be observed in SCI animals with a mean volume of 12.5 (7.61, 17.3) mm3, and no cyst-formation was present in the sham group.