Neural Regeneration Research ›› 2014, Vol. 9 ›› Issue (22): 2008-2012.doi: 10.4103/1673-5374.143436

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Evaluation of spinal cord injury animal models

Ning Zhang 1, Marong Fang 2, Haohao Chen 1, Fangming Gou 1, Mingxing Ding 1, 2   

  1. 1 Department of Medical Sciences, Jinhua Polytechnic, Jinhua, Zhejiang Province, China
    2 Institute of Neuroscience, Zhejiang University School of Medicine, Hangzhou, Zhejiang Province, China
  • Received:2014-09-08 Online:2014-11-25 Published:2014-11-25
  • Contact: Mingxing Ding, Department of Medical Sciences, Jinhua Polytechnic, Jinhua 321007, Zhejiang Province, China; Institute of Neuroscience, Zhejiang University School of Medicine, Hangzhou 310058, Zhejiang Province, China, mxding@hotmail.com.

Abstract:

Because there is no curative treatment for spinal cord injury, establishing an ideal animal model is important to identify injury mechanisms and develop therapies for individuals suffering from spinal cord injuries. In this article, we systematically review and analyze various kinds of animal models of spinal cord injury and assess their advantages and disadvantages for further studies.

Key words: nerve regeneration, spinal cord injury, animal model, establishment, evaluation, reviews, neural regeneration