Abstract:

Neuroscience, neuroprosthetics and neural regeneration would benefit from more adequate in-terfacing devices. To understand how neurons communicate, process information and control behavior, researchers need to monitor nerve cell activity with high specifity and high spatio-temporal resolution. Neural prostheses require minimally invasive implantable devices to re-place lost function, and bypass dysfunctional pathways in the nervous system. Devices built to repair damaged nerves have to support and promote regeneration of host neurons through an injured area. Finally as neuromodulation is being elevated from last resort to first choice treat-ment for an increasing number of conditions, implantable devices able to perform targeted regulation of neural activity are needed. Recent advances in device miniaturization, materials engineering and nanotechnology are enabling development of an increasing number of devices that effectively interface with neural circuits. Wireless spinal cord and deep brain stimulators, retinal and cochlear implants, high density electrodes arrays for neural recording have already proven to significantly impact fundamental research in neuroscience as well as individuals’ quality of life.