Neural Regeneration Research ›› 2016, Vol. 11 ›› Issue (2): 217-219.doi: 10.4103/1673-5374.177716
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George D. Bittner , Michelle Mikesh, Cameron L. Ghergherehchi
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This study was supported by grants from the Lone Star Paralysis Foundation and an NIH grant R01 NS081063 to GDB.
Abstract:
While the specific mechanisms responsible for retarding Wallerian degeneration and rapidly restoring behaviors lost after complete axonal severance of peripheral nerves are not yet known, PEG-fusion may translate well to clinical procedures since all drugs are benign, readily available, and are already FDA-approved for human use. Successful allograft repair suggests that tissue banks might consider the inclusion of donor nerve tissue alongside donor corneas, livers, hearts, etc. This PEG-fusion technology developed to restore many behaviors lost after peripheral nerve severance or ablation has also recently been reported to restore many behaviors lost after spinal contusion injuries.
George D. Bittner,Michelle Mikesh, Cameron L. Ghergherehchi. Polyethylene glycol-fusion retards Wallerian degeneration and rapidly restores behaviors lost after nerve severance[J]. Neural Regeneration Research, 2016, 11(2): 217-219.
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URL: https://www.sjzsyj.com.cn/EN/10.4103/1673-5374.177716
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