Neural Regeneration Research ›› 2023, Vol. 18 ›› Issue (6): 1257-1258.doi: 10.4103/1673-5374.360167

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Plasticity of callosal neurons in the contralesional cortex following traumatic brain injury

Alexandra Chovsepian, Laura Empl, Florence M. Bareyre   

  1. Institute of Clinical Neuroimmunology, Biomedical Building and Clinic of the Ludwig-Maximilians Universität München, Munich, Germany (Chovsepian A, Empl L, Bareyre FM) 
    Munich Cluster of Systems Neurology (SyNergy), Munich, Germany (Bareyre FM) 
  • Online:2023-06-15 Published:2022-12-22
  • Contact: Florence M. Bareyre, PhD, florence.bareyre@med.uni-muenchen.de.
  • Supported by:
    Work in FMB’s lab is supported by grants from the Deutsche Forschungsgemeinschaft (DFG, TRR274/1, ID 408885537, Project C03), the Wings for Life and the Humboldt foundation. FMB is also supported by the Munich Center for Systems Neurology (DFG, SyNergy; EXC 2145/ID 390857198). 

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Abstract: Traumatic brain injury (TBI) represents a significant cause of disability worldwide. It creates a vast array of damaging macro- and microscopic changes in the affected brain area(s), ranging from neuronal cell death, changes in structural spine integrity and dynamics to axonal injury and overall neuronal circuit disruption, ultimately leading to functional and cognitive deficits in both humans and animal models (Nudo, 2013).