Neural Regeneration Research ›› 2024, Vol. 19 ›› Issue (5): 973-974.doi: 10.4103/1673-5374.385305

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Is GDNF to Parkinson’s disease what BDNF is to Huntington’s disease?

Francesca R. Fusco*, Emanuela Paldino   

  1. Laboratory of Neuroanatomy, Fondazione Santa Lucia IRCCS Hospital, Rome, Italy
  • Online:2024-05-15 Published:2023-10-31
  • Contact: Francesca R. Fusco, MD, f.fusco@hsantalucia.it.

Abstract: Neurotrophic factors, or neurotrophins, are a group of molecules supporting the growth, survival, and differentiation of developing and mature neurons. Given their role in the survival of neurons, and often of specific subsets of brain cells, neurotrophins have been implicated in several ways with many neurodegenerative disorders.