Abstract: Fullerenes: The extensive development of nanoscience that has marked this century continues to evolve, producing new materials, structures, and devices for the treatments of diverse pathologies. Fullerenes are a family of nanoparticles with great applicative promise due to their small size (approximately 1 nm in diameter), structure, and capacity to cross biological barriers. Fullerene is the third pure crystal carbon form, with carbon atoms forming fused rings containing five to seven atoms that have been accidentally synthesized in 1985. This discovery led to the authors’ Nobel Prize in Chemistry award in 1996, and afterward, fullerenes were detected in nature and outer space. The Fullerene family is named after buckminsterfullerene (C60). This most famous member, in turn, is named as an homage to Buckminster Fuller, an American architect, systems theorist, author, designer, inventor, and futurist (who used similar structural principles for architectural objects he designed).