Neural Regeneration Research ›› 2025, Vol. 20 ›› Issue (5): 1401-1402.doi: 10.4103/NRR.NRR-D-24-00146

Previous Articles     Next Articles

Microglial dysfunction and genetic risk for neurodegenerative disease

Debra S. MacDonald, Jay Penney*   

  1. Department of Biomedical Sciences, AVC, University of Prince Edward Island, Charlottetown, PE, Canada
  • Online:2025-05-15 Published:2024-10-30
  • Contact: Jay Penney, PhD, jaypenney@upei.ca.
  • Supported by:
    This work was supported by a Canada Research Chair award to JP. 

Abstract: Neurodegenerattve disorders such as Alzheimer’s and Parkinson’s diseases are increasing in prevalence as world populations age. While tremendous progress has been made, our understanding of the mechanisms that underlie the development of these diseases remains far from complete. More troubling, despite the growing emottonal and ffnancial toll being taken by neurodegenerative disorders, existing treatment opttons are limited almost exclusively to those that help manage symptoms but that lack the ability to alter the progression of the disease (Liu et al., 2022).