Neural Regeneration Research ›› 2025, Vol. 20 ›› Issue (8): 2313-2314.doi: 10.4103/NRR.NRR-D-24-00388

Previous Articles     Next Articles

Brain age estimation: premise, promise, and problems

Jarrad Perron, Ji Hyun Ko*   

  1. Graduate Program in Biomedical Engineering, Price Faculty of Engineering, University of Manitoba, Winnipeg, MB, Canada (Perron J, Ko JH) PrairieNeuro Research Centre, Kleysen Institute for Advanced Medicine, Health Sciences Centre, Winnipeg, MB, Canada (Perron J, Ko JH) Department of Human Anatomy and Cell Science, Rady Faculty of Health Sciences, University of Manitoba, Winnipeg, MB, Canada (Ko JH)
  • Online:2025-08-15 Published:2024-12-13
  • Contact: Ji Hyun Ko, PhD, ji.ko@umanitoba.ca.
  • Supported by:
    This work was funded by the Natural Sciences and Engineering Research Council of Canada (RGPIN: 2016-05964 & 2023-04283 to JHK), the University of Manitoba Tri-Agency Bridge Funding (#57289 to JHK), and the Ricard Foundation’s Baxter Bursary (to JP).

PDF

17

Abstract: Premise: The combined effects of modern healthcare practices which prolong lifespan and declining birthrates have created unprecedented changes in age demographics worldwide that are especially pronounced in Japan, South Korea, Europe, and North America. Since old age is the most significant predictor of dementia, global healthcare systems must rise to the challenge of providing care for those with neurodegenerative disorders. This will be a significant global phenomenon since it is predicted that the number of people living with dementia will dramatically increase from 47 million by 2030 to 131 million by 2050 (Wimo and Prince, 2010).