Neural Regeneration Research ›› 2018, Vol. 13 ›› Issue (5): 795-796.doi: 10.4103/1673-5374.232463

Previous Articles     Next Articles

 Semaphorin 3A: from growth cone repellent to promoter of neuronal regeneration

Bor Luen Tang1, 2   

  1. 1 Department of Biochemistry, Yong Loo Lin School of Medicine, National University Health System, Medical Drive, Singapore, Singapore;
    2 Graduate School for Integrative Sciences and Engineering, National University of Singapore, Medical Drive, Singapore, Singapore
  • Received:2018-04-17 Online:2018-05-15 Published:2018-05-15
  • Contact: Bor Luen Tang, Ph.D., bchtbl@nus.edu.sg.

PDF

278

Abstract:

Semaphorin 3A is a classically known axonal guidance cue that mediates axonal growth cone repulsion and collapse. Recent works, however,suggest that it may have the apparently diametrically opposite activity of promoting neuronal regeneration.