Neural Regeneration Research ›› 2019, Vol. 14 ›› Issue (9): 1525-1526.doi: 10.4103/1673-5374.255964

Previous Articles     Next Articles

Therapeutic potential of AMPA receptor antagonist perampanel against cerebral ischemia: beyond epileptic disorders

Satoshi Suda, Kazumi Kimura   

  1. Department of Neurology, Graduate School of Medicine, Nippon Medical School, Tokyo, Japan
  • Online:2019-09-15 Published:2019-09-15
  • Contact: Satoshi Suda, MD, PhD, suda-sa@nms.ac.jp.

Abstract:

Stroke is a leading cause of mortality and severe neurological disability worldwide; however, curative therapeutic options are limited. Although recanalization therapy using endovascular thrombectomy has demonstrated great benefits in the functional outcome of patients with acute ischemic stroke, the rate of excellent clinical outcomes remains limited. Therefore, the current recanalization therapeutic approach may require adjunctive therapy to improve outcomes.