Neural Regeneration Research ›› 2012, Vol. 7 ›› Issue (5): 359-362.

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NG2 expression in rats with acute T10 spinal cord injury

Haoran Lv, Jinshun Yang, Zhuangwen Liao, Yu Zhao, Yan Huang   

  1. Department of Orthopedic Surgery, Second Affiliated Hospital of Guangzhou Medical College, Guangzhou 510260, Guangdong Province, China
  • Received:2011-09-25 Revised:2011-12-12 Online:2012-02-15 Published:2012-02-15
  • Contact: Jinshun Yang, Chief physician, Department of Orthopedic Surgery, Second Affiliated Hospital of Guangzhou Medical College, Guangzhou 510260, Guangdong Province, China dryang302@163.com
  • About author:Haoran Lv☆, Doctor, Associate professor, Department of Orthopedic Surgery, Second Affiliated Hospital of Guangzhou Medical College, Guangzhou 510260, Guangdong Province, China

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Abstract:

Rat models of T10 spinal cord injury were established with a clamp method. NG2 expression was detected with immunohistochemical staining and western blot. Ten days after spinal cord injury, the number of NG2-positive cells in the damaged areas and NG2 absorbance were both significantly increased. The findings indicate that acute T10 spinal cord injury in rats can lead to upregulation of NG2 protein expression in damaged areas.

Key words: NG2 protein, spinal cord injury, immunohistochemistry, western blot, neural regeneration