Neural Regeneration Research ›› 2022, Vol. 17 ›› Issue (7): 1623-1624.doi: 10.4103/1673-5374.330625

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Loss of smell in COVID-19: reasons for variable recovery patterns from anosmia

Abdul Mannan Baig*   

  1. Department of Biological and Biomedical Sciences, Aga Khan University, Karachi, Pakistan
  • Online:2022-07-15 Published:2022-01-18
  • Contact: Abdul Mannan Baig, MBBS, PhD, abdul.mannan@aku.edu.

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Abstract: Anosmia, which coupled with altered or loss of taste, during the current pandemic in individuals has heralded the onset of coronavirus disease 2019 (COVID-19). The recovery from the anosmia has been seen to vary among individuals, which in some cases has been seen to take a protracted course, the causes of which is unknown. Direct damages to olfactory ensheathing cells (OECs) and extensive inflammation of the olfactory mucosa (OM) has been implicated as the cause of anosmia in patients with long-COVID. Here I debate the possible mechanisms underlying the variable recovery from anosmia in COVID-19 and reasons why it continues in some patients with long-COVID?