Neural Regeneration Research ›› 2014, Vol. 9 ›› Issue (3): 280-284.doi: 10.4103/1673-5374.128223

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Quantitative volumetric analysis of the optic radiation in the normal human brain using diffusion tensor magnetic resonance imaging-based tractography

Dong-Hoon Lee1, 2, Ji-Won Park3, Cheol-Pyo Hong1   

  1. 1 Center for Medical Metrology, Division of Convergence Technology, Korea Research Institute of Standards and Science (KRISS), Daejeon,
    Republic of Korea
    2 Department of Radiological Science, College of Health Science, Yonsei University, Wonju, Republic of Korea
    3 Department of Physical Therapy, College of Medical Science, Catholic University of Daegu, Daegu, Republic of Korea
  • Received:2013-11-25 Online:2014-02-15 Published:2014-02-15
  • Contact: Cheol-Pyo Hong, Ph.D., 267 Gajeong-Ro, Yuseong-Gu, Daejeon 305-340, Republic of Korea, dosagehong@kriss.re.kr.

Abstract:

o attain the volumetric information of the optic radiation in normal human brains, we performed diffusion tensor imaging examination in 13 healthy volunteers. Simultaneously, we used a brain normalization method to reduce individual brain variation and increase the accuracy of volumetric information analysis. In addition, tractography-based group mapping method was also used to investigate the probability and distribution of the optic radiation pathways. Our results showed that the measured optic radiation fiber tract volume was a range of about 0.16% and that the fractional anisotropy value was about 0.53. Moreover, the optic radiation probability fiber pathway that was determined with diffusion tensor tractography-based group mapping was able to detect the location relatively accurately. We believe that our methods and results are helpful in the study of optic radiation fiber tract information.