Neural Regeneration Research ›› 2016, Vol. 11 ›› Issue (3): 410-411.doi: 10.4103/1673-5374.179048

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Multiple sclerosis and neuromyelitis optica spectrum disorders: some similarities in two distinct diseases

Hiroaki Yokote, Hidehiro Mizusawa   

  1. Department of Neurology, Nakano General Hospital, Tokyo, Japan Department of Neurology and Neurological Sciences, Tokyo Medical and Dental University, Tokyo, Japan (Yokote H)
    Department of Neurology, National Center of Neurology and Psychiatry, Kodaira, Tokyo, Japan (Mizusawa H)
  • Received:2016-02-20 Online:2016-03-15 Published:2016-03-15
  • Contact: Hidehiro Mizusawa, M.D., Ph.D.,mizusawa@ncnp.go.jp.

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Abstract:

There are some similarities between MS and NMOSD, although these 2 diseases are essentially distinct. Understanding the similarities between MS and NMOSD helps us to see an atypical case that is the borderline between MS and NMOSD. It is essential to choose carefully an appropriate treatment based on the nature of the lesion and the pathophysiological background: IFN-β should be avoided for this borderline patient at least since the disease can be mediated by Th17.