Neural Regeneration Research ›› 2018, Vol. 13 ›› Issue (11): 1885-1886.doi: 10.4103/1673-5374.239436

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Retinal remodeling following photoreceptor degeneration causes retinal ganglion cell death

Diego García-Ayuso, Johnny Di Pierdomenico, MartaAgudo-Barriuso, Manuel Vidal-Sanz, María P. Villegas-Pérez   

  1. Departamento de Oftalmología, Facultad de Medicina, Universidad de Murcia, and Instituto Murciano de Investigación Biosanitaria Hospital Virgen de la Arrixaca (IMIB-Virgen de la Arrixaca), Murcia, Spain
  • Received:2018-07-23 Online:2018-11-15 Published:2018-11-15
  • Contact: Diego García-Ayuso, PhD, diegogarcia@um.es.
  • Supported by:

    This work was supported by grants from Fundación Séneca, Agencia de Ciencia y Tecnología Región de Murcia (19881/GERM/15), Spanish Ministry of Economy and Competitiveness, Instituto de Salud Carlos III, Fondo Europeo de Desarrollo Regional ‘‘Una Manera de Hacer Europa’’ (SAF2015-67643-P, PI16/00380, RD16/0008/0026, PI16/00031).

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Abstract:

The retina is the extension of the central nervous system that senses light. Cones and rods, situated in the outer retina, convert light into electrical signals that travel through intermediate neurons where these are further processed until they finally reach retinal ganglion cells (RGCs). The afferent neurons of the retina, the RGCs, send the visual information through their axons in the optic nerve to the retinorecipient nuclei in the brain, where is further analysed.