Neural Regeneration Research ›› 2018, Vol. 13 ›› Issue (12): 2083-2084.doi: 10.4103/1673-5374.241448

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Do new neurons contribute to functional reorganization after brain damage?

 Clorinda Arias, Angelica Zepeda   

  1. Departamento de Medicina Genómica y Toxicología Ambiental, Instituto de Investigaciones Biomédicas, Universidad Nacional Autónoma de México, Ciudad de México, México
  • Received:2018-08-16 Online:2018-12-15 Published:2018-12-15
  • Contact: Angelica Zepeda, PhD, azepeda@biomedicas.unam.mx
  • Supported by:

    This work was supported by Consejo Nacional de Ciencia y Tecnología (CONACyT) 282470 (to AZ).

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Abstract:

The finding that adult neurogenesis occurs constitutively in the brain was a breakthrough in neuroscience and soon gained attention as a possible mechanism for neurorepair after brain damage. In a recent study we show that the dentate gyrus (DG) reorganizes anatomically over time after damage, while new neurons undergo maturation and activate in response to a contextual fear memory recall. These findings provide new evidence on the possible role of neurogenesis in cognitive recovery after brain injury.