Neural Regeneration Research ›› 2019, Vol. 14 ›› Issue (8): 1383-1384.doi: 10.4103/1673-5374.253522

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Cell-free therapy: a neuroregenerative approach to sensory neuropathy?

Afrânio Ferreira Evangelista 1,2, Milena Botelho Pereira Soares 1, Cristiane Flora Villarreal 1,2   

  1. 1Instituto Gonçalo Moniz, Fundação Oswaldo Cruz, Salvador, BA, Brazil;
    2Faculdade de Farmácia, Universidade Federal da Bahia, Salvador, BA, Brazil
  • Online:2019-08-15 Published:2019-08-15
  • Contact: Cristiane Flora Villarreal, PhD, cfv@ufba.br.

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Abstract:

Stem cells are considered as key therapeutic tools in the field of regenerative medicine. In the last decade, based on a growing body of knowledge about their mechanisms of action, a new way of exploring the therapeutic potential of stem cells without the need for cell transplantation has been evidenced. This approach, called cell-free therapy, uses stem cells as a source of therapeutic molecules rather than the therapeutic agent per se, and several studies have shown relevant therapeutic effects under a variety of experimental conditions, including nervous system disorders.