Neural Regeneration Research ›› 2021, Vol. 16 ›› Issue (2): 306-307.doi: 10.4103/1673-5374.290895

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How does chronic dry eye shape peripheral and central nociceptive systems?

Adrian Guerrero-Moreno, Darine Fakih, Stéphane Melik Parsadaniantz, Annabelle Réaux-Le Goazigo*#br#   

  1. Sorbonne Université, INSERM, CNRS, Institut de la Vision, Paris, France
  • Online:2021-02-15 Published:2020-12-03
  • Contact: Annabelle Réaux-Le Goazigo, PhD, annabelle.reaux@inserm.fr.
  • Supported by:
    This work was completed with the support of the Programme Investissements d’Avenir IHU FOReSIGHT (ANR-18-IAHU-01).

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Abstract: Dry eye disease (DED) is a multifactorial disease characterized by a loss of homeostasis of the tear film and accompanied by ocular symptoms, in which tear film instability and hyperosmolarity, ocular surface inflammation and damage, and neurosensory abnormalities play etiological roles (Belmonte et al., 2017).