Neural Regeneration Research ›› 2021, Vol. 16 ›› Issue (4): 688-689.doi: 10.4103/1673-5374.295329

Previous Articles     Next Articles

Impact of the metabolic syndrome on the evolution of neurodegenerative diseases

Ana Paula de A. Boleti, Jeeser Alves Almeida, Ludovico Migliolo*   

  1. S-InovaBiotech, Programa de Pós-Graduação em Biotecnologia, Universidade Católica Dom Bosco, Campo Grande, MS, Brazil (de A. Boleti AP, Migliolo L)
    Programa de Pós-Graduação em Ciências do Movimento, Programa de Pós-Graduação em Saúde e Desenvolvimento na Região Centro Oeste, Universidade Federal de Mato Grosso do Sul, Campo Grande, MS, Brazil (Almeida JA)
    Programa de Pós-graduação em Biologia Celular e Molecular, Programa de Pós-graduação em Bioquímica, Universidade Federal do Rio Grande do Norte, Natal, Brazil (Migliolo L)
  • Online:2021-04-15 Published:2020-12-21
  • Contact: Ludovico Migliolo, ludovico@ucdb.br.

PDF

171

Abstract: Metabolic syndrome (MetS) might be defined as the simultaneous accumulation of several functional changes that frequently occur in adults over 60 years of age (Gomez et al., 2018). The diagnosis of MetS requires the presence of three or more factors such as high body mass, type-2 diabetes mellitus (T2DM), dyslipidemia, and arterial hypertension, which increase the risk of cardiovascular diseases as well as neurological complications, as stroke and dementia (Dyken and Lacoste, 2018). Usually, these functional changes coincide and result in insensitivity for example hormones as leptin, adiponectin, and insulin (Dyken and Lacoste, 2018).