Neural Regeneration Research ›› 2022, Vol. 17 ›› Issue (7): 1473-1474.doi: 10.4103/1673-5374.330600

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Lycium barbarum polysaccharides and ferroptosis: jumping into the era of novel regulated cell death

Amy Cheuk Yin Lo*, Ming Yang   

  1. Department of Ophthalmology, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong Special Administrative Region, China
  • Online:2022-07-15 Published:2022-01-15
  • Contact: Amy Cheuk Yin Lo, PhD, amylo@hku.hk.
  • Supported by:
    This work was supported by Health and Medical Research Fund, the Food and Health Bureau, The Government of the Hong Kong Special Administrative Region (05163526, 06171516) and General Research Fund, Research Grants Council, The Government of the Hong Kong Special Administrative Region (17112919) to ACYL.

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Abstract: Lycium barbarum polysaccharides (LBP) are the key bioactive components of Lycium barbarum (also named Gouqizi or Goji berry or wolfberry), a widely used Traditional Chinese herb for more than 2000 years. Believed to balance “yin” and “yang” within the body, Lycium barbarum is consumed for general health benefits. Besides, it also “nourishes” the eyes, kidneys, lungs, and liver. Indeed, Lycium barbarum has been considered as a “superfruit”, an inexpensive supplement for many oxidative stress-related diseases. It is currently included in the Pharmacopoeia of the People’s Republic of China.