Neural Regeneration Research ›› 2022, Vol. 17 ›› Issue (11): 2551-2552.doi: 10.4103/1673-5374.339013

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Delayed activation of leg somatotopic fibers of an injured corticospinal tract in a patient with cerebral infarction

Min Jye Cho, Sung Ho Jang*   

  1. Department of Physical Medicine and Rehabilitation, College of Medicine, Yeungnam University, Namku, Daegu, Republic of Korea
  • Online:2022-11-15 Published:2022-04-23
  • Contact: Sung Ho Jang, MD, strokerehab@hanmail.net.
  • Supported by:
    This work was supported by the Medical Research Center Program (2015R1A5A2009124, to SHJ) through the National Research Foundation of Korea (NRF) funded by the Ministry of Science, ICT, and Future Planning.

Abstract: Stroke is a leading cause of major adult disabilities, and motor weakness is one of the most serious disability-related sequelae of stroke. Most of the motor recovery in stroke patients is reported to occur within 6 months after stroke onset, and this period is deemed critical for motor recovery in stroke (Grefkes and Fink, 2020; Olafson et al., 2021). Therefore, active rehabilitation within 6 months after stroke onset is strongly recommended for hemiparetic stroke patients (Grefkes and Fink, 2020; Olafson et al., 2021). Research on delayed motor recovery after the critical period is important in stroke rehabilitation because it could provide a basis for rehabilitation strategies for chronic patients who failed to show good recovery during the critical period, even though they had a potential for good motor recovery. However, little is known about delayed motor recovery occurring more than 6 months after stroke onset (Jang et al., 2019).