Neural Regeneration Research ›› 2023, Vol. 18 ›› Issue (12): 2699-2670.doi: 10.4103/1673-5374.373687

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Implication of gut microbiome in age-related macular degeneration

Wendy Luo, Dimitra Skondra*   

  1. Pritzker School of Medicine, University of Chicago, Chicago, IL, USA (Luo W)
    Department of Ophthalmology and Visual Science, University of Chicago, Chicago, IL, USA (Skondra D)
  • Online:2023-12-15 Published:2023-06-15
  • Contact: Dimitra Skondra, MD, PhD, dskondra@bsd.uchicago.edu.
  • Supported by:
    Bright Focus Foundation, UChicago Women’s Board, ISPB, UChicago ITM, Genentech ARVO Foundation, FORE-I Foundation (to DS). 

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Abstract: Age-related macular degeneration (AMD) is the most common cause of blindness in the United States in adults over 55 years of age and is one of the leading global causes of blindness: at least 196 million of the worldwide population have AMD, and prevalence is projected to rise to 288 million by 2040 (Lin et al., 2021). As cases and disease burden increase, improvements in the characterization of AMD pathobiology and exploration of potential therapeutic solutions are necessary first steps in addressing this global health concern.