Neural Regeneration Research ›› 2024, Vol. 19 ›› Issue (3): 481-482.doi: 10.4103/1673-5374.380884

Previous Articles     Next Articles

Heterogeneous patterning of blood-brain barrier and adaptive myelination as renewing key in gray and white matter

Barbara Pavan*   

  1. Department of Neuroscience and Rehabilitation, University of Ferrara, via L Borsari, Ferrara, Italy; Center for Translational Neurophysiology of Speech and Communication (CTNSC), Italian Institute of Technology (IIT), via Fossato di Mortara, Ferrara, Italy
  • Online:2024-03-15 Published:2023-09-01
  • Contact: Barbara Pavan, PhD, pvnbbr@unife.it.
  • Supported by:
    The present work was supported by Fondo per la Ricerca di Ateneo (FAR) 2022, University of Ferrara, Ferrara, Italy (to BP).

PDF

22

Abstract: Background: Development and homeostasis of the brain are enabled through the precise control of the cell microenvironment by the blood-brain barrier (BBB), which interfaces between the brain parenchyma and the lumen of blood microvessels, and by the blood-cerebrospinal fluid barrier, which separates the cerebrospinal fluid from the blood vessels of the choroid plexus (Villabona-Rueda et al., 2019). Here, the focus will be on the BBB, the impairment of which is considered the earliest common denominator in neurovascular diseases.