Abstract: Neuroregeneration is a very complex phenomenon characterized by the generation of new neurons and synapses, involving connections between adjacent cells and axonal projections. Neuroregeneration supplies additional long-term resources to replace those altered by the injury and ensure lasting functional recovery. There are substantial differences between the neurodegeneration in the peripheral nervous system (PNS) and the central nervous system (CNS) particularly in terms of extent and speed. In fact, the PNS has remarkable regenerative properties, both morphological and functional, whereas the CNS is most unable to self-repair and regenerate.