Neural Regeneration Research ›› 2024, Vol. 20 ›› Issue (2): 477-478.doi: 10.4103/NRR.NRR-D-24-00127

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Gamma oscillations and their role in orchestrating balance and communication following stroke

Montana Samantzis#, Cong Wang#, Matilde Balbi*   

  1. Queensland Brain Institute, The University of Queensland, Brisbane, QLD, Australia (Samantzis M, Wang C, Balbi M)
    Engineering Research Centre of Traditional Chinese Medicine Intelligent Rehabilitation, Ministry of Education, Shanghai, China (Wang C)
  • Online:2025-02-15 Published:2024-06-18
  • Contact: Matilde Balbi, PhD,m.balbi@uq.edu.au.
  • Supported by:
    This work was supported by the Brazil Family Program for Neurology (to MB), Alastair Rushworth Research Fund (to MS), Australian Government Research Training Program Scholarship (to MS), the National Natural Science Foundation of China (82202787) (to CW).

Abstract: Induced brain oscillations in the gamma range have recently garnered attention due to their reported neuroprotective effects in the treatment of Alzheimer’s disease. This method differs from pharmacological approaches by tapping into the neuronal population dynamics that underlie the homeostatic processes in the brain that are crucial for the recovery of function. Recently, induced gamma-range oscillations have been used to improve cerebral blood flow, motor function, and synaptic plasticity in a mouse model of focal stroke, highlighting the broad potential of recruiting intrinsic recovery processes for the treatment of neurological conditions. Addressing open questions, such as the frequency specificity of the benefits, will shed light on the intrinsic processes involved and allow clinicians to optimize recovery after stroke.