Abstract: Hypoglycemia – a critical complication linked to worsened brain function in diabetic subjects: Hypoglycemia is characterized by a decline in circulatory glucose levels below standard physiological thresholds. Mild hypoglycemia, classified as level 1 hypoglycemia, is defined by blood glucose levels below 70 mg/dL and can be effectively addressed through carbohydrate intake. Severe hypoglycemia, denoted by blood glucose levels less than 54 mg/dL, poses a life-threatening risk if left untreated. Individuals with type 1 and type 2 diabetes undergoing insulin treatment are particularly susceptible to hypoglycemia due to impaired counterregulatory mechanisms. According to International Hypoglycemia Study Group, nearly 40% of type 1 diabetic individuals and 20% of type 2 diabetic individuals with a history of insulin treatment exceeding five years may develop severe hypoglycemia as a complication. Notably, recurrent occurrences of mild hypoglycemia are more prevalent in diabetic subjects compared to instances of severe hypoglycemia (Brazeau et al., 2022).