Neural Regeneration Research ›› 2025, Vol. 20 ›› Issue (10): 2906-2908.doi: 10.4103/NRR.NRR-D-24-00691

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Immunoassay development guidelines for neurodegenerative disorders: lessons from a failed pS129-α-synuclein electrochemiluminescence immunoassay

Hash Brown Taha* , Alanna Morris   

  1. Leonard Davis School of Gerontology, University of Southern California, Los Angeles, CA, USA (Taha HB) Deparmtent of Neurobiology, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, CA, USA (Morris A)
  • Online:2025-10-15 Published:2025-02-08
  • Contact: Hash Brown Taha, hashbrown@ucla.edu.

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Abstract: An aging population is a double-edged sword. On one hand, advancements in biotechnology and healthcare allow more people to enjoy longer lives. On the other hand, increases in the aging population accompany a surge in age-associated diseases, particularly neurodegenerative disorders. Since aging is the primary risk factor for many neurodegenerative disorders, living longer does not necessarily equate to maintaining a reasonable quality of life (Feigin et al., 2020).