Neural Regeneration Research ›› 2025, Vol. 20 ›› Issue (10): 2903-2905.doi: 10.4103/NRR.NRR-D-24-00713

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Genistein: a possible solution for the treatment of Alzheimer’s disease

Karolina Pierzynowska, Bartosz Karaszewski, Grzegorz Węgrzyn*   

  1. Department of Molecular Biology, University of Gdansk, Gdansk, Poland (Pierzynowska K) Brain Diseases Centre, Medical University of Gdansk, Poland, and Department of Adult Neurology, Faculty of Medicine, Medical University of Gdansk, Gdansk, Poland (Karaszewski B) Department of Molecular Biology, University of Gdansk, Gdansk, Poland (Węgrzyn G)
  • Online:2025-10-15 Published:2025-02-08
  • Contact: Grzegorz Węgrzyn, PhD, DSc, grzegorz.wegrzyn@ug.edu.pl.
  • Supported by:
    This work was supported by Fundacja ORLEN (donation No. 161/XI/2022) (to GW).

Abstract: Neurodegenerative diseases are defined as disorders resulting from the slow and progressive loss of function and eventual death of neural cells that result from the primary pathology of nervous tissue. They can lead to severe nervous system dysfunction, eventually affecting multiple organs and systems. Several hundred neurodegenerative diseases have been described, and owing to their prevalence, severity, clinical characteristics, and generally low therapeutic efficiency, they constitute one of the greatest problems for healthcare providers and one of the heaviest issues in public health.