Neural Regeneration Research ›› 2012, Vol. 7 ›› Issue (35): 2793-2800.

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Mechanism of alpha-lipoic acid in attenuating kanamycin-induced ototoxicity

Aimei Wang1, Ning Hou1, Dongyan Bao1, Shuangyue Liu1, Tao Xu2   

  1. 1 Department of Physiology, Liaoning Medical University, Jinzhou 121001, Liaoning Province, China
    2 Scientific Laboratorial Center, Liaoning Medical University, Jinzhou 121001, Liaoning Province, China
  • Received:2012-09-07 Revised:2012-11-13 Online:2012-12-15 Published:2012-12-15
  • Contact: Wang, Department of Physiology, Liaoning Medical University, Jinzhou 121001,Liaoning Province, China aimeiwang@yahoo.com.cn
  • About author:Aimei Wang☆, Ph.D.,Professor, Department of Physiology, Liaoning Medical University, Jinzhou 121001,Liaoning Province, China

Key words: alpha-lipoic acid, kanamycin, mouse, cochlea, p38 mitogen-activated protein kinase, c-Jun
N-terminal kinase,
auditory brainstem response, phosphorylation, hearing loss, western blot;
immunohistochemistry