Neural Regeneration Research ›› 2014, Vol. 9 ›› Issue (17): 1621-1627.doi: 10.4103/1673-5374.141791

Previous Articles     Next Articles

Neuroprotective effects of Buyang Huanwu decoction on cerebral ischemia-induced neuronal damage

Qingchun Mu 1, 2, Pengfei Liu 1, Xitong Hu 1, Haijun Gao 1, Xu Zheng 1, Haiyan Huang 1   

  1. 1 First Hospital of Bethune, Jilin University, Changchun, Jilin Province, China
    2 Hongqi Hospital of Mudanjiang Medical University, Mudanjiang, Heilongjiang Province, China
  • Received:2014-08-04 Online:2014-09-16 Published:2014-09-16
  • Contact: Haiyan Huang, M.D., Ph.D., First Hospital of Bethune, Jilin University, Changchun 130021, Jilin Province, China, Huanghy@jlu.edu.cn.
  • Supported by:

    This work was supported by grants from Health and Family Planning Commission of Heilongjiang Province Research Projects, No. 2014-195 and Science and Technology Research Projects of Mudanjiang Medical University, No. ZS201305.

PDF

741

Abstract:

Among the various treatment methods for stroke, increasing attention has been paid to traditional Chinese medicines. Buyang Huanwu decoction is a commonly used traditional Chinese medicine for the treatment of stroke. This paper summarizes the active components of the Chinese herb, which is composed of Huangqi (Radix Astragali seu Hedysari), Danggui (Radix Angelica sinensis), Chishao (Radix Paeoniae Rubra), Chuanxiong (Rhizoma Ligustici Chuanxiong), Honghua (Flos Carthami), Taoren (Semen Persicae) and Dilong (Pheretima), and identifies the therapeutic targets and underlying mechanisms that contribute to the neuroprotective properties of Buyang Huanwu decoction.

Key words: nerve regeneration, Buyang Huanwu decoction, traditional Chinese medicine, cerebral ischemia, clinical application, neuroprotection, review, neural regeneration