Neural Regeneration Research ›› 2018, Vol. 13 ›› Issue (1): 65-66.doi: 10.4103/1673-5374.224370

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Diabetes, its impact on peripheral nerve regeneration: lessons from pre-clinical rat models towards nerve repair and reconstruction

Kirsten Haastert-Talini1, 2, Lars B. Dahlin3, 4   

  1. 1 Institute of Neuroanatomy and Cell Biology, Hannover Medical School, Hannover, Germany;
    2 Center for Systems Neuroscience (ZSN), Hannover, Germany;
    3 Department of Translational Medicine–Hand Surgery, Lund University, Lund, Sweden;
    4 Department of Hand Surgery, Skåne University Hospital, Malmö, Sweden
  • Received:2017-12-15 Online:2018-01-15 Published:2018-01-15
  • Contact: Kirsten Haastert-Talini, DVM, Ph.D.,

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Abstract:

The global number of patients with type 1 and type 2 diabetes is about to increase substantially in the coming decades. The reasons for this are two-fold, at first there is actual increase in incidence of type 1 diabetes and at second there is global increase in living expectancy and a high prevalence of patients with type 2 diabetes among the elderly. The diabetic condition is affiliated with reduced peripheral nervous system maintenance, such as peripheral neuropathies (Juster-Switlyk and Smith, 2016) that may be more common in men.