中国神经再生研究(英文版) ›› 2019, Vol. 14 ›› Issue (9): 1525-1526.doi: 10.4103/1673-5374.255964

• 观点:脑损伤修复保护与再生 • 上一篇    下一篇

AMPA受体拮抗剂吡仑帕奈对脑缺血的治疗潜力:不只治疗癫痫病

  

  • 出版日期:2019-09-15 发布日期:2019-09-15

Therapeutic potential of AMPA receptor antagonist perampanel against cerebral ischemia: beyond epileptic disorders

Satoshi Suda, Kazumi Kimura   

  1. Department of Neurology, Graduate School of Medicine, Nippon Medical School, Tokyo, Japan
  • Online:2019-09-15 Published:2019-09-15
  • Contact: Satoshi Suda, MD, PhD, suda-sa@nms.ac.jp.

摘要:

orcid: 0000-0002-7242-2005 (Satoshi Suda)

Abstract:

Stroke is a leading cause of mortality and severe neurological disability worldwide; however, curative therapeutic options are limited. Although recanalization therapy using endovascular thrombectomy has demonstrated great benefits in the functional outcome of patients with acute ischemic stroke, the rate of excellent clinical outcomes remains limited. Therefore, the current recanalization therapeutic approach may require adjunctive therapy to improve outcomes.