中国神经再生研究(英文版) ›› 2021, Vol. 16 ›› Issue (3): 587-590.doi: 10.4103/1673-5374.293151

• 原著:脊髓损伤修复保护与再生 • 上一篇    下一篇

改善帕金森病患者的非运动症状:综合康复训练的意义

  

  • 出版日期:2021-03-15 发布日期:2020-12-17
  • 基金资助:

    这项研究得到了意大利卫生部的资助

Anxiety, depression, and quality of life in Parkinson’s disease: the implications of multidisciplinary treatment

Viviana Lo Buono, Rosanna Palmeri, Simona De Salvo, Matteo Berenati, Agata Greco, Rosella Ciurleo, Chiara Sorbera, Vincenzo Cimino, Francesco Corallo*, Placido Bramanti, Silvia Marino, Giuseppe Di Lorenzo, Lilla Bonanno#br#   

  1. Department of Neurobioimaging, Istituto di Ricovero e Cura a Carattere Scientifico IRCCS Centro Neurolesi Bonino-Pulejo, Messina, Italy
  • Online:2021-03-15 Published:2020-12-17
  • Contact: Francesco Corallo, francesco.corallo80@yahoo.it.
  • Supported by:
    This study was supported by a grant from the Italian Health Minister, No. GR-2013-02359069.

摘要:

帕金森病引起的焦虑和抑郁情绪降低了患者的生活质量,以及运动技能和认知能力。为了解多学科协作康复训练对PD患者焦虑、抑郁和生活质量的影响,此项自身对照观察性研究于2017年1月至2018年12月纳入完成60d住院综合康复计划的100例PD患者,包括男49例和女51例,平均年龄64.66岁。综合康复计划包括运动训练、言语治疗和认知干预。结果发现60d的综合康复训练改善了PD患者的功能状态,并对其情绪和日常生活活动能力有积极作用,同时可提高患者生活质量。因而,综合康复训练对于帕金森病非运动症状不失为一种可选择的干预策略。该研究已于2016年6月获得Carattere Scientifico科学研究中心(IRCCS)神经病学中心“ Bonino-Pulejo”伦理委员会批准(批准号6/2016)。

https://orcid.org/0000-0003-4862-3832 (Francesco Corallo)

Abstract: Anxiety and depression in Parkinson’s disease (PD) reduce well-being of the patients. Emotional alterations influence motor skills and cognitive performance; moreover, they contribute significantly and independently to worsen rehabilitative treatment response. We investigated anxiety, depression, and quality of life in PD patients subjected to multidisciplinary rehabilitative training. The self-controlled study included 100 PD patients (49 males and 51 females with the mean age of 64.66 years) admitted to 60 days hospitalization rehabilitative program, between January 2017 and December 2018. Motor, cognitive, linguistic abilities, and functional independence were evaluated at admission (T0 baseline visit) and 60 days after (T1) the multidisciplinary rehabilitation including motor exercises, speech therapies, and cognitive intervention. The multidisciplinary rehabilitation improved functional status in PD patients and exerted its positive effects on mood, motor abilities, autonomy in the activities of daily life, perception of quality of life, cognitive performance and speech skills. Non-motor symptoms may worsen severe disability and reduce quality of life. They are often poorly recognized and inadequately treated. Nonetheless, multidisciplinary rehabilitative training represents an optimal strategy to improve disease management. The study was approved by Istituito di Ricovero e Cura a Carattere Scientifico (IRCCS) Centro Neurolesi “Bonino-Pulejo” Ethical Committee (approval No. 6/2016) in June 2016. 

Key words: anxiety, depression, multidisciplinary rehabilitation, Parkinson’s disease