中国神经再生研究(英文版) ›› 2021, Vol. 16 ›› Issue (4): 672-673.doi: 10.4103/1673-5374.293139

• 观点:脑损伤修复保护与再生 • 上一篇    下一篇

预防和治疗脑瘫的再生医学

  

  • 出版日期:2021-04-15 发布日期:2020-12-21

Prevention and treatment of cerebral palsy with cord blood stem cells and cord-derived mesenchymal stem cells

Haruo Shintaku*   

  1. Donated Course “Disability medicine and Regenerative medicine”, Osaka City University Graduate School of Medicine, Osaka, Japan
  • Online:2021-04-15 Published:2020-12-21
  • Contact: Haruo Shintaku, MD, PhD, shintakuh@med.osaka-cu.ac.jp.
  • Supported by:


摘要: https://orcid.org/0000-0002-1677-1593 (Haruo Shintaku)

Abstract: Perinatal asphyxia is a well-known medical condition that can lead to CP. Several etiologies are involved in this process, but the primary cause is hypoxic-ischemic encephalopathy (HIE) that is characterized by reduced blood flow and oxygen supply to the baby’s brain. CP is one of the possible consequences of this neurologic injury. Once developed, CP is difficult to treat, and the role of rehabilitation in functional recovery is still limited. The Neonatal Resuscitation Program is one of the various approaches that have been tried to date. The program has been providing training courses since 2006 for midwives and nurses in addition to physicians, and we saw a marked reduction in mortality associated with birth asphyxia just after a year of the program. However, further efforts are required to achieve 0% mortality.