中国神经再生研究(英文版) ›› 2021, Vol. 16 ›› Issue (6): 1031-1036.doi: 10.4103/1673-5374.300448

• 原著:脊髓损伤修复保护与再生 • 上一篇    下一篇

连续重复运动想象诱发的疲劳会降低皮质脊髓兴奋性

  

  • 出版日期:2021-06-15 发布日期:2020-12-31

Corticospinal excitability during motor imagery is diminished by continuous repetition-induced fatigue

Akira Nakashima1, 2, Takefumi Moriuchi2, Daiki Matsuda2, Takashi Hasegawa2, Jirou Nakamura2, Kimika Anan2, Katsuya Satoh2, Tomotaka Suzuki3, Toshio Higashi2, *, Kenichi Sugawara3#br#   

  1. 1 Department of Rehabilitation, Juzenkai Hospital, Nagasaki, Japan;  2 Graduate School of Biomedical Sciences, Nagasaki University, Nagasaki, Japan;  3 School of Rehabilitation, Kanagawa University of Human Services, Yokosuka, Japan
  • Online:2021-06-15 Published:2020-12-31
  • Contact: Toshio Higashi, PhD, higashi-t@nagasaki-u.ac.jp.

摘要:

连续重复的运动想象可以改善运动训练的效果,但运动想象训练的干预时间应合理控制,因为其可能会导致大脑的疲劳。为阐明连续重复的运动想象致中枢神经系统疲劳的情况,设计了2个试验。在实验1中,14名健康青年受试者执行了想象手抓紧并举起装500 mL或1500 mL水的1.5升塑料瓶,两种动作连续完成100次,两种动作任务时间间隔为48h。在该实验中,观察到在1500 mL的条件下受试者精神产生疲劳,且捏力下降;每组动作之间连续进行运动想象时,专注力或皮质脊髓兴奋性之间存在变化。因此,在实验2中,12名健康受试者执行了200次想象抓举装满1500 mL的1.5升塑料瓶的任务;在这种条件下,观察到专注力和皮质脊髓兴奋性降低。研究结果提示,连续运动想象除了可产生精神疲劳外,还可使皮质脊髓束兴奋性降低。

https://orcid.org/0000-0002-4562-068X (Toshio Higashi)

Abstract: Application of continuous repetition of motor imagery can improve the performance of exercise tasks. However, there is a lack of more detailed neurophysiological evidence to support the formulation of clear standards for interventions using motor imagery. Moreover, identification of motor imagery intervention time is necessary because it exhibits possible central fatigue. Therefore, the purpose of this study was to elucidate the development of fatigue during continuous repetition of motor imagery through objective and subjective evaluation. The study involved two experiments. In experiment 1, 14 healthy young volunteers were required to imagine grasping and lifting a 1.5-L plastic bottle using the whole hand. Each participant performed the motor imagery task 100 times under each condition with 48 hours interval between two conditions: 500 mL or 1500 mL of water in the bottle during the demonstration phase. Mental fatigue and a decrease in pinch power appeared under the 1500-mL condition. There were changes in concentration ability or corticospinal excitability, as assessed by motor evoked potentials, between each set with continuous repetition of motor imagery also under the 1500-mL condition. Therefore, in experiment 2, 12 healthy volunteers were required to perform the motor imagery task 200 times under the 1500-mL condition. Both concentration ability and corticospinal excitability decreased. This is the first study to show that continuous repetition of motor imagery can decrease corticospinal excitability in addition to producing mental fatigue. This study was approved by the Institutional Ethics Committee at the Nagasaki University Graduate School of Biomedical and Health Sciences (approval No. 18121302) on January 30, 2019.

Key words: central nervous system, concentration, continuous repetition of motor imagery, corticospinal excitability, mental fatigue, motor evoked potential, motor imagery, muscle fatigue, neurophysiology, transcranial magnetic stimulation