中国神经再生研究(英文版) ›› 2022, Vol. 17 ›› Issue (11): 2551-2552.doi: 10.4103/1673-5374.339013

• 影像图片 • 上一篇    

脑梗死患者损伤皮质脊髓束的腿部体感纤维的延迟激活

  

  • 出版日期:2022-11-15 发布日期:2022-04-23

Delayed activation of leg somatotopic fibers of an injured corticospinal tract in a patient with cerebral infarction

Min Jye Cho, Sung Ho Jang*   

  1. Department of Physical Medicine and Rehabilitation, College of Medicine, Yeungnam University, Namku, Daegu, Republic of Korea
  • Online:2022-11-15 Published:2022-04-23
  • Contact: Sung Ho Jang, MD, strokerehab@hanmail.net.
  • Supported by:
    This work was supported by the Medical Research Center Program (2015R1A5A2009124, to SHJ) through the National Research Foundation of Korea (NRF) funded by the Ministry of Science, ICT, and Future Planning.

摘要:

脑卒中是造成成人重大残疾的主要原因,而运动无力是脑卒中最严重的残疾相关后遗症之一。据报道,脑卒中患者的大部分运动恢复发生在脑卒中发病后的6个月内,这个时期被认为是脑卒中运动恢复的关键时期。因此,强烈建议偏瘫的脑卒中患者在发病后6个月内进行积极的康复训练。对关键期后延迟运动恢复的研究在卒中康复中非常重要,因为它可以为那些在关键期未能表现出良好恢复的慢性患者提供康复策略的依据,尽管他们有可能获得良好的运动恢复。然而,人们对脑卒中发病后6个月以上发生的延迟运动恢复知之甚少。 此研究报道了1例脑梗死患者在发病后表现出腿部运动功能恢复延迟,弥散张量纤维束成像(DTT)和经颅磁刺激(TMS)证实了损伤皮质脊髓束(CST)的腿部体感纤维的激活。

https://orcid.org/0000-0001-6383-5505 (Sung Ho Jang)

Abstract: Stroke is a leading cause of major adult disabilities, and motor weakness is one of the most serious disability-related sequelae of stroke. Most of the motor recovery in stroke patients is reported to occur within 6 months after stroke onset, and this period is deemed critical for motor recovery in stroke (Grefkes and Fink, 2020; Olafson et al., 2021). Therefore, active rehabilitation within 6 months after stroke onset is strongly recommended for hemiparetic stroke patients (Grefkes and Fink, 2020; Olafson et al., 2021). Research on delayed motor recovery after the critical period is important in stroke rehabilitation because it could provide a basis for rehabilitation strategies for chronic patients who failed to show good recovery during the critical period, even though they had a potential for good motor recovery. However, little is known about delayed motor recovery occurring more than 6 months after stroke onset (Jang et al., 2019).