中国神经再生研究(英文版) ›› 2012, Vol. 7 ›› Issue (2): 137-140.
• 综述:退行性病与再生 • 上一篇 下一篇
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Yi Tan, Yulin Deng, Hong Qing
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Alzheimer’s disease is characterized by two pathological hallmarks: amyloid plaques and neurofibrillary tangles. In addition, calcium homeostasis is disrupted in the course of human aging. Recent research shows that dense plaques can cause functional alteration of calcium signals in mice with Alzheimer’s disease. Calcium channel blockers are effective therapeutics for treating Alzheimer’s disease. This review provides an overview of the current research of calcium channel blockers involved in Alzheimer’s disease therapy.
Key words: Alzheimer’s disease, calcium channel, calcium homeostasis, Alzheimer’s disease pathogenesis, β-amyloid, calcium channel blocker
. Calcium channel blockers and Alzheimer’s disease[J]. 中国神经再生研究(英文版), 2012, 7(2): 137-140.
Yi Tan, Yulin Deng, Hong Qing. Calcium channel blockers and Alzheimer’s disease[J]. Neural Regeneration Research, 2012, 7(2): 137-140.
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