中国神经再生研究(英文版) ›› 2012, Vol. 7 ›› Issue (32): 2542-2547.

• 原著:脑损伤修复保护与再生 • 上一篇    下一篇

擅长认知重评者认知重评调节负性情绪的神经基础

  

  • 收稿日期:2012-04-10 修回日期:2012-09-08 出版日期:2012-11-15 发布日期:2012-11-15

Neural bases of reappraisal regulatory effect on negative emotion in high reappraisers

Wencai Zhang1, Jin Luo 1, 2   

  1. 1 Key Laboratory of Mental Health, Institute of Psychology, Chinese Academy of Sciences, Beijing 100101, China
    2 Beijing Key Laboratory of Learning and Cognition, Department of Psychology, Capital Normal University, Beijing 100048, China
  • Received:2012-04-10 Revised:2012-09-08 Online:2012-11-15 Published:2012-11-15
  • Contact: Jin Luo, M.D., Professor, Key Laboratory of Mental Health,Institute of Psychology,Chinese Academy of Sciences, Beijing 100101,China; Beijing Key Laboratory of Learning and Cognition, Department of Psychology, Capital Normal University, Beijing 100048,China luoj@psych.ac.cn;luoj@cnu.edu.cn
  • About author:Wencai Zhang☆, M.D.,Associate researcher, Key Laboratory of Mental Health,Institute of Psychology,Chinese Academy of Sciences, Beijing 100101,China

Abstract:

Previous studies have reported that individual differences in reappraisal use are associated with particular patterns of neural activity. We hypothesized that if ‘high reappraisers’ (individuals who use reappraisal well in a behavioral experiment) completed two training sessions, they would exhibit more reliable patterns of neural activity related to cognitive reappraisal. In the present study, 13 high reappraisers were selected from 27 healthy volunteers through an initial behavioral experiment (first training) followed by a functional MRI experiment (second training). Emotional images selected from the International Affective Picture System were used for both the behavioral and functional MRI sessions of the experiment. The behavioral results revealed that reappraisal reduced subjective unpleasantness. The functional MRI results revealed that the cognitive reappraisal used by high reappraisers decreased the activation of emotion-responsive regions, including the amygdala,insula, and cingulate gyrus, and increased the activation of regulation-related regions, including the inferior prefrontal cortex, orbital prefrontal cortex, and dorsal medial prefrontal cortex. These findings suggest the involvement of inferior orbital and dorsal medial prefrontal cortex in constructing reappraisal strategies that modulate activity in emotion-processing systems.

Key words: cognitive reappraisal, negative emotion, amygdala, functional MRI, neural regeneration