周围神经损伤

Hypoxic pre-conditioned adipose-derived stem/progenitor cells embedded in fibrin conduits promote peripheral nerve regeneration in a sciatic nerve graft model

• Figure 2｜Descriptive nerve morphology. 

  

  In all groups, no coaptation failure or neuroma formation was found macroscopically when the nerve segments were harvested at 16 weeks. Descriptive evaluation of toluidine blue-stained nerve cross-sections showed that the number of axons, axon size and myelinization appeared to be reduced in animals in the AT (Figure 2B) and ATC groups (Figure 2C) compared with animals in the ATCN (Figure 2C) and ATCH groups (Figure 2E). Connective tissue distribution appeared less in the ATCH group than that in the other three groups. However, the nerve morphology in all pathologic specimens (Figure 2B’–E’) was clearly different compared with the healthy contralateral side (Figure 2A).

  
  

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发布日期： 2022-08-29  浏览： 184