Neural Regeneration Research ›› 2013, Vol. 8 ›› Issue (17): 1551-1559.doi: 10.3969/j.issn.1673-5374.2013.17.002

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Lentivirus carrying the Atoh1 gene infects normal rat cochlea

Song Pan1, Jingzhi Wan2, Shaosheng Liu3, Song Zhang1, Hao Xiong4, Jun Zhou1, Wu Xiong1, Kunfei Yu1, Yong Fu5   

  1. 1 Department of Otolaryngology, Guangming New District People’s Hospital, Shenzhen 518106, Guangdong Province, China
    2 Department of Surgery, Hubei University of Science and Technology, Xianning 437100, Hubei Province, China
    3 Department of Otolaryngology, Beilun Branch of the First Affiliated Hospital, College of Medicine, Zhejiang University, Ningbo 315800, Zhejiang Province, China
    4 Department of Otolaryngology, Second Affiliated Hospital, Sun Yat-sen University, Guangzhou 510120, Guangdong Province, China
    5 Department of Otolaryngology, First Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou 310003, Zhejiang Province, China
  • Received:2012-10-31 Revised:2013-04-24 Online:2013-06-15 Published:2013-06-15
  • Contact: Yong Fu, M.D., Associate professor, Associate chief physician, Department of Otolaryngology, First Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou 310003, Zhejiang Province, China, fyent@163.com.
  • About author:Song Pan☆, M.D., Attending physician.

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Key words: neural regeneration, gene therapy, Atoh1, lentivirus, hair cells, myosin 7a, cochlea, auditory threshold, grants-supported paper, neuroregeneration