Neural Regeneration Research ›› 2012, Vol. 7 ›› Issue (33): 2600-2606.

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Heat-sensitive moxibustion attenuates the inflammation after focal cerebral ischemia/reperfusion injury

Aijiao Xiao1, Rixin Chen2, Mingfei Kang2, Shenghai Tan3   

  1. 1 Basal Medical College of Jiangxi University of Traditional Chinese Medicine, Nanchang 330004, Jiangxi Province, China
    2 Affiliated Hospital of Jiangxi University of Traditional Chinese Medicine, Nanchang 330006, Jiangxi Province, China
    3 Jiangxi University of Traditional Chinese Medicine, Nanchang 330004, Jiangxi Province, China
  • Received:2012-07-05 Revised:2012-10-07 Online:2012-11-25 Published:2012-11-25
  • Contact: Aijiao Xiao, Basal Medical College of Jiangxi University of Traditional Chinese Medicine, Nanchang 330004,Jiangxi Province, China xaj527@163.com
  • About author:Aijiao Xiao☆, M.D.,Associate professor, Basal Medical College of Jiangxi University of Traditional Chinese Medicine, Nanchang 330004, Jiangxi Province,China

Abstract:

Heat-sensitive moxibustion has neuroprotective effects against focal cerebral ischemia/reperfusion injury, however its mechanism of action remains unclear. In this study, rat models of focal cerebral ischemia/reperfusion injury were treated with suspended moxibustion at acupoint Dazhui (DU14) for 35 minutes. Results showed that suspended moxibustion decreased infarct volume, reduced cortical myeloperoxidase activity, and suppressed serum levels of proinflammatory cytokines in rats with focal cerebral ischemia/reperfusion injury. Our experimental findings indicated that heat-sensitive moxibustion can attenuate inflammation and promote repair after focal cerebral ischemia/reperfusion injury.

Key words: suspended moxibustion, heat-sensitive moxibustion, traditional suspended moxibustion, middle cerebral artery occlusion, cerebral ischemia/reperfusion injury, infarct volume, proinflammatory cytokines, interleukin, myeloperoxidase, traditional Chinese medicine, neural regeneration