中国神经再生研究(英文版) ›› 2014, Vol. 9 ›› Issue (7): 693-700.doi: 10.4103/1673-5374.131568

• 观点:脑损伤修复保护与再生 • 上一篇    下一篇

外伤性脑损伤后的可塑性成像

  

  • 收稿日期:2014-04-10 出版日期:2014-04-15 发布日期:2014-04-15

Imaging brain plasticity after trauma

Zhifeng Kou 1, 2, Armin Iraji 1   

  1. 1 Department of Biomedical Engineering, Wayne State University, Detroit, MI, USA
    2 Department of Radiology, Wayne State University, Detroit, MI, USA
  • Received:2014-04-10 Online:2014-04-15 Published:2014-04-15
  • Contact: Zhifeng Kou, Ph.D., Department of Biomedical Engineering, Wayne State University, Detroit, MI 48201, USA, zhifeng_kou@wayne.edu.

摘要:

大脑在脑卒中或癫痫后具有极高的可塑性; 然而,有关创伤性脑损伤(TBI)后大脑可塑性的研究仍旧缺乏。美国韦恩州立大学的Zhifeng Kou教授从磁共振成像视角总结回顾了外伤性脑损伤患者大脑可塑性的最近证据。与其他形式的后天脑损伤类似,脑外伤患者也表现出两种结构性重组,以及由其他脑区进行的功能代偿。然而,脑外伤后的大规模脑神经网络重建仍旧是未知数。

Abstract:

The brain is highly plastic after stroke or epilepsy; however, there is a paucity of brain plasticity investigation after traumatic brain injury (TBI). This mini review summarizes the most recent evidence of brain plasticity in human TBI patients from the perspective of advanced magnetic resonance imaging. Similar to other forms of acquired brain injury, TBI patients also demonstrated both structural reorganization as well as functional compensation by the recruitment of other    brain regions. However, the large scale brain network alterations after TBI are still unknown, and the field is still short of proper means on how to guide the choice of TBI rehabilitation or treatment plan to promote brain plasticity. The authors also point out the new direction of brain plasticity investigation.