中国神经再生研究(英文版) ›› 2015, Vol. 10 ›› Issue (8): 1231-1233.doi: 10.4103/1673-5374.162752

• 观点:脑损伤修复保护与再生 • 上一篇    下一篇

心电图与脑功能:眼球跟踪评估创伤性损伤及脑功能的变化

  

  • 收稿日期:2015-05-25 出版日期:2015-08-24 发布日期:2015-08-24

A new tool for monitoring brain function: eye tracking goes beyond assessing attention to measuring central nervous system physiology

Uzma Samadani   

  1. Steven and Alexandra Cohen Veterans Center for Post-Traumatic Stress and Traumatic Brain Injury at NYU Langone Medical Center; Departments of Neurosurgery, Psychiatry, Physiology and Neuroscience, New York University School of Medicine, New York; New York Harbor Health Care System, USA
  • Received:2015-05-25 Online:2015-08-24 Published:2015-08-24
  • Contact: Uzma Samadani, M.D., Ph.D., F.A.C.S., uzma@samadani.com.

摘要:

震荡和其他形式的脑损伤,如颅内压增高,痴呆和无数的其他损害神经系统功能的原因并不总是可以用常规手段检测出的。缺乏准确的诊断、生物标记物和治疗结果等相关措施会给病症带来毁灭性影响。我们从个别患者中发现,自我用药可能有药物成瘾的危险,业务活动受损,进而造成社会关系失败。没有准确的诊断就不可能知道的问题是如何发生的,并无法评估其社会影响。目前仍缺乏对可进入临床试验创伤性脑损伤患者结果评估的适当分类方案,这给试验治疗和药物开发造成很大阻碍。最近,我们出版了两篇描述震荡走势,创伤性脑脑损和其他神经病理学眼动追踪的有效新算法。眼动跟踪并不是单纯的描述外观或电活动,其可以评估脑功能,并因此代表了评估中枢神经系统完整性的一个相对较新的模式。我们研究小组发表的这两篇文章与几乎所有之前眼动追踪出版物之间的区别是,这两篇文章利用了非空间校准的眼动跟踪。而不是评估哪些人选择看,跟踪眼睛如何移动的措施。

Abstract:

A new tool for monitoring brain function: eye tracking goes beyond assessing attention to measuring central nervous system physiology
Concussion and other forms of brain injury, elevated intracranial pressure, dementia and myriadother function-impairing neurologic conditions are not always detectable with conventional means. The lack of accurate diagnostics, biomarkers, and outcome measures has a devastating impact. Individual patients may suffer in obscurity, self-medicate into an addictive spiral, have impaired professional activity, and develop failed interpersonal relationships. Without accurate diagnostics it is impossible to know the incidence of the problem or assess its societal impact. The lack of appropriate classification schemes and objective outcome measures for patients entering clinical trials for concussion and other forms of traumatic brain injury (TBI) contributes to the failure of such trials for therapeutics and prophylactics at great expense to the research and development community and those it hopes to serve, including athletes, students and hapless victims of trauma. Recently Dr. Uzma Samadani’s group published two manuscripts describing a novel algorithm for eye tracking that will be useful for concussion, other forms of TBI and other neuropathologies. Eye tracking assesses brain function rather than appearance or electrical activity, and thus represents a relatively newer modality for assessment of central nervous system integrity. The difference between the two papers published by their group and nearly all prior eye tracking publications, is that these new papers utilize non-spatially calibrated eye tracking. Rather than assess what someone chooses to look at, the tracking measures how well the eyes are capable of moving.