中国神经再生研究(英文版) ›› 2017, Vol. 12 ›› Issue (5): 714-722.doi: 10.4103/1673-5374.206634

• 综述:脊髓损伤修复保护与再生 • 上一篇    下一篇

脊髓损伤下肢肌肉横断面积的MRI检查及临床意义

  

  • 收稿日期:2017-04-25 出版日期:2017-05-15 发布日期:2017-05-15
  • 基金资助:

    退伍军人事务部,退伍军人健康管理局,康复研究与发展处基金

MRI analysis and clinical significance of lower extremity muscle cross-sectional area after spinal cord injury

Robert M. Lester1, Kori Johnson1, Refka E. Khalil1, Rehan Khan3, Ashraf S. Gorgey1, 2   

  1. 1 Spinal Cord Injury and Disorders Center, Hunter Holmes McGuire Veterans Administration Medical Center (VAMC), Richmond, VA, USA; 2 Department of Physical Medicine and Rehabilitation, Virginia Commonwealth University, Richmond, VA, USA; 3 Radiology Service, Hunter Holmes McGuire Veterans Administration Medical Center (VAMC), Richmond, VA, USA
  • Received:2017-04-25 Online:2017-05-15 Published:2017-05-15
  • Contact: Ashraf S. Gorgey, M.P.T., Ph.D., ashraf.gorgey@va.gov.
  • Supported by:

    The work is supported by the Department of Veteran Affairs, Veteran Health Administration, Rehabilitation Research and Development Service (B7867-W).

摘要:

 

脊髓损伤后不久,肌肉骨骼和静脉系统经历一系列的还原性变化,特别是在损伤平面以下的变化更为明显。流动性减小和机械卸载引发肌肉尺寸和骨矿物质含量的适应性降低。肌肉的大小和力量的丧失以及脊髓损伤后的静注量增加,大大减少了机械关节压迫的次数,这为骨骼提供了有益的生物力学应力。骨质疏松后骨质疏松的机械负荷降低可使瘫痪患者骨密度迅速下降。运动,阻力训练和电刺激可以诱导肌肉肥大,并减少慢性脊髓损伤后的骨质。使用各种成像技术,包括计算机断层扫描(CT)和磁共振成像(MRI)来确定运动程序的有效性。

文中研究旨在总结使用MRI手动追踪下肢肌肉的方法学。尽管肌肉质量差,IMF增加,目标肌肉的解剖学边界发生变化,但对于进行分析所需的详细程序,这一点非常重要。我们还打算分析脊髓损伤患者小腿肌肉横断面积及其与肌肉骨骼和静脉功能的关系。

 

 

Abstract:

Shortly after spinal cord injury (SCI), the musculoskeletal system undergoes detrimental changes in size and composition, predominantly below the level of injury. The loss of muscle size and strength, along with increased immobility, predisposes persons with SCI to rapid and severe loss in bone mineral density and other health related consequences. Previous studies have highlighted the significance of measuring thigh muscle cross-sectional area, however, measuring the size and composition of muscles of the lower leg may provide insights on how to decrease the risk of various comorbidities. The purpose of the current review was to summarize the methodological approach to manually trace and measure the muscles of the lower leg in individuals with SCI, using magnetic resonance imaging. We also intend to highlight the significance of analyzing lower leg muscle cross-sectional area and its relationship to musculoskeletal and vascular systems in persons with SCI.

Key words: spinal cord injury, magnetic resonance imaging, pressure ulcers, venous thromboembolism, cardiovascular disease, bone health