中国神经再生研究(英文版) ›› 2018, Vol. 13 ›› Issue (9): 1530-1533.doi: 10.4103/1673-5374.237113

• 综述:神经损伤修复保护与再生 • 上一篇    下一篇

促进神经外科手术后的轴突再生:超声治疗神经损伤的一个视角

  

  • 收稿日期:2018-06-28 出版日期:2018-09-15 发布日期:2018-09-15

Promoting axonal regeneration following nerve surgery: a perspective on ultrasound treatment for nerve injuries

Konstantin D. Bergmeister, Simeon C. Daeschler, Patrick Rhodius, Philipp Schoenle, Arne Böcker, Ulrich Kneser, Leila Harhaus   

  1. Department of Hand, Plastic and Reconstructive Surgery, Burn Center, Department of Plastic and Hand Surgery, University of Heidelberg, BG Trauma Hospital Ludwigshafen, Ludwigshafen, Germany
  • Received:2018-06-28 Online:2018-09-15 Published:2018-09-15
  • Contact: Konstantin D. Bergmeister,M.D., Ph.D.,konstantin.bergmeister@bgu-ludwigshafen.de.

摘要:

orcid:0000-0003-3910-9727(Konstantin D. Bergmeister)

Abstract:

Nerve injury is often associated with limited axonal regeneration and thus leads to delayed or incomplete axonal reinnervation. As a consequence of slow nerve regeneration, target muscle function is often insufficient and leads to a lifelong burden. Recently, the diagnosis of nerve injuries has been improved and likewise surgical reconstruction has undergone significant developments. However, the problem of slow nerve regeneration has not been solved. In a recent meta-analysis, we have shown that the application of low-intensity ultrasound promotes nerve regeneration experimentally and thereby can improve functional outcomes. Here we want to demonstrate the experimental effect of low intensity ultrasound on nerve regeneration,the current state of investigations and its possible future clinical applications.