中国神经再生研究(英文版) ›› 2019, Vol. 14 ›› Issue (4): 593-594.doi: 10.4103/1673-5374.247463

• 观点:视神经损伤修复保护与再生 • 上一篇    下一篇

间接性外伤性视神经病变:在闭合性头部创伤的背景下建模视神经损伤

  

  • 出版日期:2019-04-15 发布日期:2019-04-15

Indirect traumatic optic neuropathy: modeling optic nerve injury in the context of closed head trauma

Emma G. Burke 1, Shelby M. Cansler 2, Nathan K. Evanson 2, 3   

  1. 1 Medical College of Georgia, Augusta University, Augusta, GA, USA;
    2 Division of Pediatric Rehabilitation Medicine, Cincinnati Children’s Hospital, Cincinnati, OH, USA;
    3 Department of Pediatrics, University of Cincinnati, Cincinnati, OH, USA
  • Online:2019-04-15 Published:2019-04-15
  • Contact: Nathan K. Evanson, MD, PhD, Nathan.evanson@cchmc.org.
  • Supported by:

    This work was supported by NIH grant HD001097 (to NKE) and by a Cincinnati Children’s Hospital Procter Scholar Award (to NKE).

摘要:

orcid: 0000-0003-2474-9764 (Nathan K. Evanson)

Abstract:

Traumatic optic neuropathy: Traumatic brain injury is one of the leading causes of disability and mortality in the United States. It impacts people of all ages and demographics, particularly younger males and members of the military. Vision loss is commonly associated with traumatic brain injuries of all severities and can leave patients permanently disabled. This vision loss can be caused by injury to the visual system at multiple levels, including the eyes, optic nerves, and many different sites in the brain and brainstem. Despite the far-reaching effects of visual impairment after traumatic brain injury, its incidence after traumatic brain injury is not well measured, and few successful treatments have been identified or implemented.